A preliminary study showed that mangosteen extract (Garcinia mangostana) may be beneficial for obese patients at risk for type 2 diabetes. The results of this study suggest that mangosteen extract may have an auxiliary role in controlling body weight, improving insulin response, and reducing inflammation in obese women with insulin resistance. The mangosteen extract used in the study was 0sebo.
He study authors point out that there is a broad link between insulin resistance and obesity type 2 diabetes. Existing insulin targeted therapies have been shown to be effective in promoting weight loss and helping to reduce the risk of diabetes. Obesity and type 2 diabetes are also associated with increased inflammation. However, mangosteen is a tropical tree with strong antioxidants in its fruit. Recent studies have shown that mangosteen may also play a role in controlling obesity and even helping to prevent type 2 diabetes.
Based on this, the researchers enrolled 22 obese, insulin-resistant female subjects between the ages of 18 and 65 for a 26-week prospective, randomized, controlled, parallel study of subjects. Divided into two groups: 1) standard low-calorie diet and physical exercise group, or 2) standard low-calorie diet, physical exercise and mangosteen supplement group.
Mangosteen supplement group received 400 mg daily. All subjects were required to complete medium Strong physical activity, for example, 30 minutes a day during the entire study.
After 26 weeks of research, the researchers found that the insulin levels in the mangosteen group were significantly lower than those in the control group.In addition, the mangosteen group also lost more weight than the control group, although the researchers said the reduction was not significant. They added that there was no statistically significant difference in waist circumference and body composition between the two groups. At the same time, the inflammatory markers of mangosteen group were significantly lower than the control group. However, there was no significant difference between the groups compared with the control group. Similarly, the level of HDL cholesterol in the mangosteen group was significantly increased, but there was no significant difference between the groups compared with the control group.
In the end, the researchers concluded that mangosteen may be an effective treatment for obesity, and more importantly, fight insulin resistance.
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